| Carolina at Atlanta | 1:00 PM | FOX | Tickets | Travel | Georgia Dome |
| Minnesota at Detroit | 1:00 PM | FOX | Tickets | Travel | Ford Field |
| Cincinnati at Green Bay | 1:00 PM | CBS | Tickets | Travel | Lambeau Field |
| Houston at Tennessee | 1:00 PM | CBS | Tickets | Travel | LP Field |
| Oakland at Kansas City | 1:00 PM | CBS | Tickets | Travel | Arrowhead Stadium |
| New England at NY Jets | 1:00 PM | CBS | Tickets | Travel | Giants Stadium |
| New Orleans at Philadelphia | 1:00 PM | FOX | Tickets | Travel | Lincoln Financial Field |
| St. Louis at Washington | 1:00 PM | FOX | Tickets | Travel | FedEx Field |
| Arizona at Jacksonville | 1:00 PM | FOX | Tickets | Travel | Jacksonville Stadium |
| Tampa Bay at Buffalo | 4:05 PM | FOX | Tickets | Travel | Ralph Wilson Stadium |
| Seattle at San Francisco | 4:05 PM | FOX | Tickets | Travel | Candlestick Park |
| Pittsburgh at Chicago | 4:15 PM | CBS | Tickets | Travel | Soldier Field |
| Baltimore at San Diego | 4:15 PM | CBS | Tickets | Travel | Qualcomm Stadium |
| Cleveland at Denver | 4:15 PM | CBS | Tickets | Travel | Invesco Field at Mile High |
| NY Giants at Dallas | 8:20 PM | NBC | Tickets | Travel | Cowboys Stadium |
| MON, SEP 21 | TIME (ET) | TV | RESOURCES | LOCATION |
| Indianapolis at Miami | 8:30 PM |
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